Yuk-Ching Tse-Dinh

Distinguished University Professor, Florida International University

Biomolecular Sciences Institute; Chemistry and Biochemistry

Office: AHC4 210

Phone: 305-348-4956

Email: ytsedinh@fiu.edu

Conference Website: 2024 Topoismerases in Biology and Medicine Conference

Curriculum Vitae


Research Areas

Organizer of upcoming international conference on Topoisomerases in Biology and Medicine

  • The structure and function of DNA topoisomerases as the basis for discovery of antibacterial and anticancer drug leads from synthetic molecules and natural products

View Dr. Tse-Dinh's peer-reviewed publications

Publications with undergraduate coauthors (*)

  • Garcia PK, *Martinez Borrero R, Annamalai T, *Diaz E, *Balarezo S, Tiwari PB, Tse-Dinh YC. Localization of Mycobacterium tuberculosistopoisomerase I C-terminal sequence motif required for inhibition by endogenous toxin MazF4. Front Microbiol. 2022;13:1032320.  
  • Diaz B, *Mederos C, Tan K, Tse-Dinh YC. Microbial Type IA Topoisomerase C-Terminal Domain Sequence Motifs, Distribution and Combination. Int J Mol Sci. 2022;23(15):8709. 
  • Sandhaus S, Annamalai T, Welmaker G, Houghten RA, *Paz C, Garcia PK, *Andres A, Narula G, Rodrigues Felix C, Geden S, Netherton M, Gupta R, Rohde KH, Giulianotti MA, Tse-Dinh YC. Small-Molecule Inhibitors Targeting Topoisomerase I as Novel Antituberculosis Agents. Antimicrob Agents Chemother. 2016;60(7):4028-36. 




  • Hollins University, Virginia BA 1977 Chemistry
  • Harvard University, Massachusetts PhD 1982 Biological Chemistry