- The structure and function of DNA topoisomerases as the basis for discovery of antibacterial and anticancer drug leads from synthetic molecules and natural products
Recent publications/abstracts with undergraduate coauthors (*)
- *Yang J, Annamalai T, Cheng B, Banda S, Tyagi R, Tse-Dinh YC. Antimicrobial Susceptibility and SOS-dependent Increase in Mutation Frequency are Impacted by E. coli Topoisomerase I C-terminal Point Mutation. Antimicrob Agents Chemother 2015 Oct;59(10):6195-202.
- *Paz C, Annamalai T, Tse-Dinh YC. Screening for Novel Leads Towards Antibacterial Compounds Targeting Topoisomerase Ia, a New Target Found in All Bacteria, Annual Biomedical Research Conference for Minority Students, San Antonio, TX, September 2014.
- Annamalai T, *Parra C, Tse-Dinh YC. A novel assay to identify antibacterial compounds targeting bacterial topoisomerase I. SE Regional Meeting of the American Chemical Society, Atlanta, GA, November 2013.
- Hollins University, Virginia BA 1977 Chemistry
- Harvard University, Massachusetts PhD 1982 Biological Chemistry