Research Areas
Organizer of upcoming international conference on Topoisomerases in Biology and Medicine
- The structure and function of DNA topoisomerases as the basis for discovery of antibacterial and anticancer drug leads from synthetic molecules and natural products
View Dr. Tse-Dinh's peer-reviewed publications
Publications with undergraduate coauthors (*)
- Garcia PK, *Martinez Borrero R, Annamalai T, *Diaz E, *Balarezo S, Tiwari PB, Tse-Dinh YC. Localization of Mycobacterium tuberculosistopoisomerase I C-terminal sequence motif required for inhibition by endogenous toxin MazF4. Front Microbiol. 2022;13:1032320.
- Diaz B, *Mederos C, Tan K, Tse-Dinh YC. Microbial Type IA Topoisomerase C-Terminal Domain Sequence Motifs, Distribution and Combination. Int J Mol Sci. 2022;23(15):8709.
- Sandhaus S, Annamalai T, Welmaker G, Houghten RA, *Paz C, Garcia PK, *Andres A, Narula G, Rodrigues Felix C, Geden S, Netherton M, Gupta R, Rohde KH, Giulianotti MA, Tse-Dinh YC. Small-Molecule Inhibitors Targeting Topoisomerase I as Novel Antituberculosis Agents. Antimicrob Agents Chemother. 2016;60(7):4028-36.
Education
- Hollins University, Virginia BA 1977 Chemistry
- Harvard University, Massachusetts PhD 1982 Biological Chemistry