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Yuk-Ching Tse-Dinh

Title: Director of the Biomolecular Sciences Institute; Distinguished University Professor

Office: AHC4 210

Phone: 305-348-4956


Curriculum Vitae

Department(s): Biomolecular Sciences Institute, Chemistry and Biochemistry

Lab: AHC4 243 — 305-348-4961


  • Hollins University, Virginia B.A. 1977 Chemistry
  • Harvard University, Massachusetts Ph.D. 1982 Biological Chemistry

Research Areas

  • The structure and function of DNA topoisomerases as the basis for discovery of antibacterial and anticancer drug leads from synthetic molecules and natural products

Tse-Dinh Lab


View Dr. Tse-Dinh's peer-reviewed publications

Recent publications/abstracts with undergraduate coauthors (*)

  • *Yang J, Annamalai T, Cheng B, Banda S, Tyagi R, Tse-Dinh YC. Antimicrobial Susceptibility and SOS-dependent Increase in Mutation Frequency are Impacted by E. coli Topoisomerase I C-terminal Point Mutation. Antimicrob Agents Chemother 2015 Oct;59(10):6195-202.
  • *Paz C, Annamalai T, Tse-Dinh YC. Screening for Novel Leads Towards Antibacterial Compounds Targeting Topoisomerase Ia, a New Target Found in All Bacteria, Annual Biomedical Research Conference for Minority Students, San Antonio, TX, September 2014.
  • Annamalai T, *Parra C, Tse-Dinh YC. A novel assay to identify antibacterial compounds targeting bacterial topoisomerase I. SE Regional Meeting of the American Chemical Society, Atlanta, GA, November 2013.